This article addresses the input legitimacy of the British EU membership referendum of 2016.It considers who was given a vote in the first place, and whether those given a vote could make a reasonable choice in light of the campaign.More precisely, it assesses the following four criteria: the franchise, the presence of clarity, the amount and quali

The importance of chromatin environment for DNA repair has gained increasing recognition in recent years.The nucleolus is the largest sub-compartment within the nucleus: it has distinct biophysical properties, selective protein retention, and houses the specialized ribosomal RNA genes (collectively referred to as rDNA) with a unique chromatin compo

The minimally invasive biomarkers that can facilitate a rapid dose assessment are valuable for the early medical treatment when accidental or occupational radiation exposure happens.Our previous proteomic research identified one kind of circulating protein, Insulin-like Growth Factor Binding Protein 3 (IGFBP-3), which showed a significant increase

IntroductionBipolar disorder is characterized by severe mood symptoms including major depressive and manic episodes.During manic episodes, many patients show cognitive dysfunction.Dopamine and glutamate are important for cognitive processing, thus the COMT and DAOA genes that modulate the expression of these neurotransmitters are of interest for st

Recent studies have emphasized the role of microglia in the progression of many neurodegenerative diseases.The colony stimulating factors, CSF-1 (M-CSF), granulocyte-macrophage CSF (GM-CSF) and granulocyte CSF (G-CSF) regulate microglia through different cognate receptors.While the receptors for GM-CSF (GM-CSFR) and G-CSF (G-CSFR) L-Carnitine are s